ASSIGNMENT AND ASSUMPTION OF DEED OF EASEMENT

     THIS ASSIGNMENT AND ASSUMPTION OF DEED OF EASEMENT (this "Assignment
Agreement") is made as of this 12TH day of JUNE, 2001, by and between MOYER
PACKING COMPANY, P.O. Box 395, Souderton, Franconia Township, Montgomery County,
Pennsylvania 18964 ("Assignor") and BIOPURE CORPORATION, a Delaware corporation
with a principal place of business at 11 Hurley Street, Cambridge, Massachusetts
02141 ("Assignee").

                              W I T N E S S E T H:

     WHEREAS, Assignor and Assignee are parties to that certain Agreement dated
October 21, 1994, as amended pursuant to that certain Amendment to Agreement
dated November 1, 1999, and that certain Second Amendment to Agreement of even
date herewith (collectively, the "Supply Agreement");

     WHEREAS, pursuant to the Supply Agreement, Assignee constructed a
Separation Facility on the Land;

     WHEREAS, pursuant to the Supply Agreement, Assignee disposes of certain
waste from the Separation Facility into the System via a private sanitary sewer
line ("Private Sewer Line");

     WHEREAS, a portion of the Private Sewer Line is located on the lands of
Nelson S. Souder, pursuant to that certain Deed of Easement by and between
Assignor and Nelson S. Souder, dated December 21, 1994 ("Deed of Easement"), a
copy of which is attached hereto as EXHIBIT "A" and made a part hereof;

     WHEREAS, pursuant to the Supply Agreement, Assignee granted to Assignor a
stock option (the "Option") to purchase 80,000 shares of the Common Stock of
Assignor. The consideration to be paid by Assignor for the Option shares is good
and marketable title to the Assets, which Assets include, among other things,
the Waste Disposal Rights; and

     WHEREAS, Assignor has exercised the Option, and desires to assign to
Assignee, all of Assignor's right, title and interest in and to the Deed of
Easement, upon the terms and conditions set forth herein.

     NOW, THEREFORE, for and in consideration of the sum of One Thousand Dollars
($1,000.00), and other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, and intending to be legally bound
hereby, the parties hereby agree as follows:

     1. CONSTRUCTION. Capitalized terms used herein and not otherwise defined
herein, shall have the meaning ascribed to such terms in the Supply Agreement.
The recitals set forth at the beginning of this Assignment Agreement shall be
deemed to be an integral part of this Assignment Agreement, and are hereby
incorporated in this Assignment Agreement.


<PAGE>   2


     2. ASSIGNMENT OF RIGHTS. Assignor hereby assigns all of its right, title
and interest in and to the Deed of Easement to Assignee unless, and until such
time as, the agreements in Article III of the Supply Agreement terminate. At
such time as the agreements in Article III of the Supply Agreement terminate,
all of Assignee's right, title and interest in and to the Deed of Easement shall
revert back to Assignor, and, in such event and at such time, Assignee agrees to
execute such documents as shall be necessary and reasonably requested by
Assignor in confirmation of the foregoing provisions of this Section 2.

     3. ASSUMPTION OF OBLIGATIONS. Assignee hereby accepts the assignment of the
Deed of Easement and undertakes and assumes the performance of the duties and
obligations of Assignor thereunder, accruing or arising after the date hereof.

     4. DEFAULT. A party shall be in default under this Assignment Agreement if
said party fails to observe or perform its respective duties and obligations
under this Assignment Agreement and/or the Deed of Easement, and such failure
continues for a period of fifteen (15) days after written notice from the
non-breaching party, or if such observance or performance is not capable of
being accomplished within such time, then within such additional reasonable time
as may be necessary, provided that the cure is commenced during such fifteen
(15) day period and diligently prosecuted to completion as soon as possible, and
in no event later than sixty (60) days after the initial notice of default. In
the event of a default, the non-breaching party shall be entitled to exercise
all of its rights and remedies provided under this Assignment Agreement, at law,
in equity, or otherwise, each such remedy being considered cumulative. No single
exercise of a remedy shall be deemed an election to forego any other remedy and
any failure to pursue a remedy shall not prevent, restrict or otherwise modify
its exercise subsequently. In the event that a party is in default under this
Assignment Agreement (and such default is not cured within the time frame set
forth above) more than two (2) times in any period of twenty four (24)
consecutive months, the non-breaching party may terminate this Assignment
Agreement.

     5. INDEMNIFICATION.

          (a) INDEMNIFICATION BY ASSIGNEE. Assignee hereby agrees to indemnify,
defend and hold harmless Assignor, and Assignor's successors and assigns, from
and against all losses, liabilities, claims, demands, causes of action, damages,
fines, fees, costs, including reasonable attorneys fees, whether or not covered
by insurance, arising out of, resulting from or caused by Assignee, or its
agents or employees, invitees or licensees, by exercise of its rights and
privileges under this Assignment Agreement or failure to comply with the
provisions of this Assignment Agreement.

          (b) INDEMNIFICATION BY ASSIGNOR. Assignor hereby agrees to indemnify,
defend and hold harmless Assignee, and Assignee's successors and assigns, from
and against all losses, liabilities, claims, demands, causes of action, damages,
fines, fees, costs, including reasonable attorneys fees, whether or not covered
by insurance, arising out of, resulting from or caused by Assignor, or its
agents, employees, or invitees under this Assignment Agreement.

          (c) This Section 5 shall survive termination and/or expiration of this
Assignment Agreement, the Deed of Easement and/or the easement granted therein.


                                       2

<PAGE>   3


     6. NOTICE. All notices and other communications which are to be given under
this Assignment Agreement shall be given in accordance with the notice
provisions set forth in the Supply Agreement.

     7. AMENDMENT. This Assignment Agreement may not be changed or amended,
except by a writing signed by each of the parties hereto.

     8. FURTHER ASSURANCES. The parties shall from time to time do and perform
such additional acts and execute and deliver such additional documents and
instruments as may be required or reasonably requested by any party to effect
the intents and purposes of this Assignment Agreement.

     9. MISCELLANEOUS. This Assignment Agreement contains the entire
understanding of Assignor and Assignee with respect to the subject matter hereof
and supersedes and cancels any and all prior negotiations, discussions and
agreements between Assignor and Assignee with respect thereto. Each and every
provision of this Assignment Agreement has been mutually negotiated, prepared
and drafted, and in connection with the construction of any provision hereof, no
consideration shall be given to the issue of which party actually prepared,
drafted, requested or negotiated any provision of this Assignment Agreement or
its deletion.

         IN WITNESS WHEREOF, the parties hereto have executed this Assignment
Agreement as of the date first above written.

                                            ASSIGNOR:
                                            MOYER PACKING COMPANY

Attest:                                     By: /s/ William G. Morral
       -----------------------------            --------------------------------
Name:                                       Name: William G. Morral
     -------------------------------              ------------------------------
Title:                                      Title: Senior Vice President and CFO
      ------------------------------               -----------------------------

(CORPORATE SEAL)


                                            ASSIGNEE:
                                            BIOPURE CORPORATION

Attest:                                     By: /s/ Francis H. Murphy
       -----------------------------            --------------------------------
Name:                                       Name: Francis H. Murphy
     -------------------------------              ------------------------------
Title:                                      Title: CFO
      ------------------------------              -----------------------------

(CORPORATE SEAL)


                                       3



<PAGE>   4


COMMONWEALTH OF PENNSYLVANIA:
                            :  ss.
COUNTY OF MONTGOMERY        :

     On the 12th day of JUNE, A.D. 2001, before me, a Notary Public for the
above County and Commonwealth of Pennsylvania, personally appeared WILLIAM G.
MORRAL, who acknowledged herself/himself to be the SENIOR VICE PRESIDENT AND CFO
of MOYER PACKING COMPANY, a corporation, and that she/he as such officer, being
authorized to do so, executed the foregoing instrument for the purposes therein
contained by signing the name of the corporation by herself/himself as SENIOR
VICE PRESIDENT AND CFO.

     IN WITNESS WHEREOF, I have hereunto set my hand and official seal.



                                  ---------------------------------
                                  Notary Public



                                       4


<PAGE>   5


STATE OF PENNSYLVANIA:
                     :  ss.
COUNTY OF MONTGOMERY :

     On the 12TH day of JUNE, A.D. 2001, before me, a Notary Public for the
above County and State of PENNSYLVANIA, personally appeared FRANCIS H. MURPHY,
who acknowledged herself/himself to be the CFO of BIOPURE CORPORATION, a
corporation, and that she/he as such officer, being authorized to do so,
executed the foregoing instrument for the purposes therein contained by signing
the name of the corporation by herself/himself as CFO.

     IN WITNESS WHEREOF, I have hereunto set my hand and official seal.


                                  ----------------------------------
                                  Notary Public




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Source: OneCLE Business Contracts.